Illumina NovaSeq: Next-Gen DNA Sequencing Platform

The Illumina NovaSeq platform is at the top of next-generation sequencing tech. It offers fast, high-throughput sequencing. This system is changing the game in biological sciences by making detailed genomic analysis possible.

It supports advanced research and clinical diagnostics. This means better data and faster discoveries. Illumina NovaSeq is a game-changer.

Key Takeaways

  • The NovaSeq 6000 System provides scalable throughput suitable for a range of genomic applications.
  • Advanced chemistry, optics, and informatics contribute to its exceptional speed, data quality, and scalability.
  • Optimized reagent kits increase cluster density and read length, enhancing sequencing quality.
  • The system enables comprehensive genomic profiling with a large pan-cancer panel and up-to-date exome enrichment for human whole-exome sequencing.
  • Streamlined RNA-Seq kits allow for the analysis of both coding and non-coding transcriptomes.
  • Pre-filled reagent cartridges and flow cells facilitate ease of use and seamless workflow integration.
  • Unique dual indexes provide increased throughput and cost-saving benefits.

Introduction to the Illumina NovaSeq Platform

The Illumina NovaSeq platform is a big step forward in genomics. It’s fast and can handle a lot of data. It can change its output based on what you need, making it great for many uses.

The illumina sequencer can produce a lot of data. It can go from 65–80 Gb to 2400–3000 Gb. This lets researchers do many different kinds of sequencing, like studying human genomes or looking at exomes or transcriptomes.

The illumina sequencing technology is very accurate. It keeps a high percentage of bases above Q30, from ≥ 75% to ≥ 90%. This is important for detailed genetic studies. The time it takes to run also varies, from ~13 hr to ~44 hr.

The illumina platform is great for doing a lot of sequencing at once. It has different flow cell formats for various needs. It also uses 2-channel chemistry for efficient reads of all DNA bases.

The NovaSeq system uses special technology to increase its speed and output. This makes it cheaper to sequence, especially with the NovaSeq X. It supports read lengths of 50, 100, and 150 for paired-end formats, which suits many sequencing needs.

How Illumina NovaSeq is Revolutionizing Genomic Data Analysis

The Illumina NovaSeq platform is changing the game in genomic data analysis. It offers unmatched deep and broad coverage capabilities. Researchers in many fields, like genome sequencing and oncology, use it to uncover complex genetic information. They get a full view of DNA and RNA.

The NovaSeq X series can make over 20,000 whole genomes per year. This is 2.5 times more than before. It speeds up finding new genetic insights and clinical information. Researchers can now explore genetic data more deeply than ever.

The NovaSeq X also has New XLEAP-SBS™ chemistry. This makes sequencing twice as fast and up to three times more accurate. It gives researchers quicker and more reliable results.

With high-resolution optics and ultra-high density flow cells, NovaSeq X boosts throughput by 2.5 times. This lowers costs and lets researchers study more genetics. It makes big studies possible with high accuracy and depth.

Illumina shows its commitment to the environment with NovaSeq X. It has 90% less packaging weight and 50% less plastic than the NovaSeq 6000. Shipping reagents at room temperature also saves nearly 500 tons of dry ice a year. This cuts down on waste and environmental harm.

Illumina also made NovaSeq X work with on-board DRAGEN™ Bio-IT and ORA compression. This means fast and accurate secondary analysis. It’s a big step in handling complex data without losing accuracy. This helps in analyzing more genomic data deeply and broadly.

Statistic Benefit
20,000 whole genomes per year 2.5 times throughput, accelerating genomic discovery
New XLEAP-SBS™ chemistry 2x higher speed, up to 3x greater accuracy
90% reduction in packaging weight Promotes sustainability
50% reduction in plastic usage Reduces environmental impact
5x lossless data compression Efficient handling of complex data sets
500 tons of dry ice savings per year Reduces waste streams for customers

Features and Specifications of the NovaSeq 6000 System

The Illumina NovaSeq 6000 system was released in March 2017. It’s known for its high-throughput sequencing capabilities. It comes in models like S1, S2, S4, and SP, offering flexibility and efficiency.

The system is praised for its deep sequencing outputs. For example, the NovaSeq 6000 v1.5 Reagent Kits can produce 65-80 Gb for 2 × 50 bp to 325-400 Gb for 2 × 250 bp sequencing. Run times vary, showing the system’s efficiency and adaptability.

Illumina also focuses on high data quality. The v1.0 and v1.5 reagent kits ensure quality scores of ≥ 85% for 2 × 50 bp and ≥ 75% for 2 × 250 bp reads. This shows the NovaSeq 6000’s precision in high-throughput sequencing capabilities.

Model Maximum Output per Run (Gb) Read Length Run Time (hours)
S1 500.00 2 x 150 bp 13 to 25
S2 1250.00 2 x 150 bp 16 to 36
S4 3000.00 2 x 150 bp 14 to 44
SP 400.00 2 x 150 bp 13 to 34

The NovaSeq 6000 system meets various sequencing needs. It can handle whole-genome sequencing to targeted gene panels. It produces reads per run from 6.67 billion in the S2 model to 20 billion in the S4 model. This makes it essential for researchers needing high-throughput sequencing capabilities.

In conclusion, the Illumina NovaSeq 6000 system delivers detailed genetic information efficiently. It provides substantial data output and deep sequencing precision. It’s a key tool in advancing genomic research, meeting a wide range of sequencing needs.

Applications of Illumina NovaSeq in Genetic Analysis

The Illumina NovaSeq platform is key in genetic analysis, especially with Whole-Genome Sequencing. It’s designed for big sequencing projects. This makes it a leader in genomics and more.

The NovaSeq shines in Whole-Genome Sequencing. It lets researchers read an organism’s whole genetic code. This gives deep insights for medical research, studying biodiversity, and personalized medicine.

By sequencing a genome, scientists find genetic links to diseases. They also learn about evolution and trait inheritance. This is done with great accuracy.

The NovaSeq also excels in RNA Sequencing (RNA-Seq). RNA-Seq is a new way to study gene activity. It shows which genes are active at any time, helping us understand cell behavior and disease.

RNA-Seq is great for seeing how genes work in different situations. This includes how cancer grows and how our immune system works.

Illumina NovaSeq also helps with epigenetic analysis. Epigenetics looks at DNA and histone changes. It shows how genes are controlled without changing the DNA itself.

Epigenetic markers tell us about gene activity. This helps us understand aging, development, and disease risk. It’s a key part of biology.

Flow Cell Data Output (Tb) Paired End Reads (B) Run Time (hours)
S2 ≥ 1 ≥ 6.67 ≤ 40
S4 ≥ 3 ≥ 20 ≤ 45

The NovaSeq 6000 supports many research and diagnostic uses. It does Whole-Genome Sequencing, RNA-Seq, and more. This makes it useful for many fields.

Its power and flexibility make the NovaSeq a key tool in genetic analysis. It helps make new discoveries and deepen our understanding of life’s genetics.

Advantages of Using the Illumina NovaSeq for High-Throughput Sequencing

Using the novaseq sequencer brings many benefits, especially for high-throughput sequencing. A big plus is the Illumina sequencing technology‘s ability to scale. This lets researchers do more and do it faster.

The NovaSeq X Series shows this scalability well. It lets you sequence deeper to find rare variants or include more samples. For example, it has 10B and 25B flow cells, making it much more efficient.

Here is a comparison table showing the NovaSeq X Series’ throughput benefits:

Flow Cell Throughput Applications
1.5B ~120,000 single cells Single-cell RNA sequencing
10B ~800,000 single cells Large-scale genetic studies
25B 2 million single cells Deep sequencing of large cohorts

Switching to the NovaSeq X 25B flow cell lets you sequence 2.5 times more samples. This is a big boost in throughput. Also, the NovaSeq X Series can analyze up to 64 human whole genomes per flow cell. This is great for studying rare diseases.

Efficiency is another big plus. The NovaSeq X Series has streamlined workflows. This means fewer steps from planning to analysis. It makes sequencing faster and reduces errors, boosting productivity.

The novaseq sequencer also excels in identifying coding variants for large groups. It can sequence about 750 exomes per 25B flow cell. This makes sequencing 128 human whole genomes per run possible. It also simplifies data analysis with DRAGEN onboard.

The Illumina sequencing technology is versatile, as shown by the NovaSeq 6000 System. It supports many sequencing methods, like whole-genome sequencing and RNA sequencing. It also works with various Illumina library kits for different applications.

Comparison Between NovaSeq 6000 and NovaSeq X Plus Systems

In the world of genomic sequencing, the NovaSeq 6000 and NovaSeq X Plus Systems stand out. The NovaSeq X Plus brings new improvements to a well-established technology. This new system is a big step up from the NovaSeq 6000.

It’s important for researchers to know the differences between these systems. The NovaSeq 6000 System Specifications offer a detailed solution for sequencing. The NovaSeq X Plus takes it even further.

Feature NovaSeq 6000 NovaSeq X Plus
Flow Cell Capacity S4 Flow Cell 25B Flow Cell
Sample Analysis Volume 2.5× more samples
Whole Genome Sequencing Up to 64 genomes per flow cell Up to 128 genomes per run
Exome Sequencing Volume ~750 exomes per flow cell
Run Time Approximately 48 hours for 25B flow cell
Single Cell Sequencing Up to 2 million cells per run
Efficiency 2.5 times more cells in half the time
Data Analysis DRAGEN onboard for enhanced efficiency
Application Support Germline and somatic WGS, WES, WTS, methylation
Workflow Streamlined with fewer touchpoints

The NovaSeq X Plus brings big improvements. It has more throughput, faster sequencing, and easier data analysis. Sequencing up to 128 human genomes per run shows its power for big projects.

Research projects, like those by the Ontario Institute for Cancer Research, use the NovaSeq X Plus. This shows its role in genetic analysis. The NovaSeq X Plus is a top choice, offering better performance and efficiency than the NovaSeq 6000.

Innovations in Sequencing Technology with NovaSeq

The Illumina NovaSeq series is a big step forward in next-generation sequencing. It brings new features that make genomic research better. One key improvement is XLEAP-SBS Chemistry, which makes sequencing faster and more accurate.

This chemistry shows Illumina’s dedication to improving sequencing. It’s a big leap in making sequencing more precise and efficient.

The NovaSeq X Series also has a special technology. It’s called patterned flow cell technology. This tech helps sequence more data by arranging clusters in billions of nanowells.

With this tech, the NovaSeq X Series can sequence up to 64 human whole genomes at once. This is a huge boost for studying rare diseases and other genomic studies.

The NovaSeq X Series is also better for the environment. It uses 90% less packaging waste and is 50% lighter than the NovaSeq 6000. It also uses 50% less plastic.

These changes help the environment and make shipping easier. They’ve cut down on dry ice usage by nearly 500 tons a year.

The NovaSeq X Series also has new features like onboard DRAGEN™ Bio-IT and ORA compression. These make analyzing data easier and faster. They also compress data by 5x without losing quality.

In the first quarter of 2023, over 200 NovaSeq X systems were ordered worldwide. This shows how popular the NovaSeq platform is. It’s being used by researchers and clinicians in many countries.

To learn more about NovaSeq’s growth and innovation, check out this Illumina press release.

Key Innovations NovaSeq X Details
XLEAP-SBS Chemistry 2x speed, up to 3x accuracy
Patterned Flow Cell Technology Even spacing of sequencing clusters
Environmental Benefits 90% reduction in packaging waste, 50% reduction in plastic usage
Dry Ice Reduction 500 tons annually
Onboard DRAGEN™ Bio-IT Automated secondary analysis with 5x lossless data compression

Data Analysis Capabilities of the Illumina NovaSeq Platform

The Illumina NovaSeq platform makes big data analysis easier. It has fewer manual steps and can handle more data at once. This lets researchers spend more time on interpreting results, not just processing data.

The NovaSeq system’s run times vary based on the analysis type. For example, BCL Convert takes about 1 hour and 30 minutes. RNA analysis also takes around the same time. Methylation analysis, however, takes about 5 hours and 15 minutes. This shows the system’s flexibility in different workflows.

DRAGEN, integrated into the NovaSeq platform, offers big benefits. It reduces FASTQ file sizes by up to 80% through compression. It also compresses genomic data by up to 5×, saving up to 80% on storage costs. These savings can add up to $1M USD over 5 years for the NovaSeq X System, and up to $1.7M USD for the NovaSeq X Plus System.

The Illumina DRAGEN secondary analysis is very accurate. It achieved 99.83% accuracy in the 2020 PrecisionFDA v2 Truth Challenge Benchmark Data. This high accuracy is crucial for reliable sequencing data analysis, ensuring researchers can trust their results.

The NovaSeq platform is also great at generating data. It offers scalable high-throughput sequencing with outputs ranging from 280–350 Gb to 2400–3000 Gb. The NovaSeq 6000 system can produce up to 667–833 Gb in a single flow cell run, doubling in dual flow cell runs.

The system efficiently handles primary, secondary, and tertiary data analysis. Illumina sequencing systems use RTA software during sequencing cycles, automating much of the process. Illumina also provides user-friendly bioinformatics tools for DNA and RNA sequencing data analysis, covering alignment, variant calling, data visualization, and total RNA expression profiling.

Additionally, the DRAGEN Bio-IT Platform excels in fast and robust secondary analysis of NGS data. It supports various datasets like whole genomes, exomes, germline, somatic datasets, and RNA sequencing. With BaseSpace Sequence Hub, a comprehensive genomics cloud computing solution, the NovaSeq platform offers seamless data management and bioinformatic analysis capabilities, suitable for labs at all stages of NGS operations.

Feature Details
Manual Touch Points 4× reduction compared to standalone solutions
Run Time (10B Flow Cell) 1 hr 30 min for BCL Convert; 1 hr 30 min for RNA analysis; 5 hr 15 min for Methylation analysis
FASTQ File Sizes Reduction Up to 80% with built-in compression
Data Storage Cost Reduction Up to 80% reduction with 5× ORA genomic data compression
5-Year Savings $1M USD for NovaSeq X; $1.7M USD for NovaSeq X Plus
Secondary Analysis Accuracy 99.83% (PrecisionFDA v2 Truth Challenge Benchmark Data)
Output Range 280–350 Gb to 2400–3000 Gb for different read lengths and samples
S4 Read Length Output 667–833 Gb (single flow cell run)
Data Analysis Stages Primary, Secondary, Tertiary

The Workflow of the Illumina NovaSeq System

The Illumina NovaSeq System is known for its efficient workflow. It has three main phases: library preparation, sequencing, and data storage and analysis.

The first step is library preparation. The TruSeq DNA PCR-Free protocol is flexible. It offers low sample (LS) and high sample (HS) protocols for different needs. The LS protocol can handle 24 samples at once, while the HS protocol can handle up to 96 samples.

After library preparation, the sequencing starts. The NovaSeq 6000 System can sequence one or two flow cells at a time. The NovaSeq Xp workflow requires less library input, making sequencing more efficient. Patterned flow cells also improve performance by increasing cluster density and data output.

Then, the system moves to data storage and analysis. The Real-Time Analysis (RTA) software in the NovaSeq 6000 System is key. It tracks run quality and stores metrics as InterOp files. These data points help with detailed analysis using apps like the BaseSpace Sequence Hub and the DRAGEN Germline Pipeline.

“The comprehensive design of the NovaSeq workflow ensures that every step from library preparation to data analysis is seamless and efficient, providing high-quality results for a variety of genomic studies.”

Finally, Illumina recommends uploading sequencing data to the BaseSpace Sequence Hub. The guide provides details on storage needs per run.

Protocol Type Sample Capacity Read Lengths
TruSeq DNA PCR-Free LS 24 samples 1x300bp, 2x150bp
TruSeq DNA PCR-Free HS 96 samples 2x250bp
NovaSeq S1 Single/Double Flow Cells 1x300bp
NovaSeq S2 Single/Double Flow Cells 2x150bp

Cost-effectiveness of the Illumina NovaSeq Platform

The Illumina NovaSeq platform is made for cost-effective sequencing. Since 2013, the cost-per-genome has dropped by 96%. This makes sequencing more affordable for many research projects.

The price of the NovaSeq is flexible. This helps labs control their spending. Next-Generation Sequencing (NGS) is becoming popular because it’s scalable and powerful. It’s great for discovering new things and can replace other methods in some studies.

  • It has lower running costs, with prices adjusted for different projects.
  • It has great product support, with 96% customer satisfaction and fast repair times.
  • It’s easy to use, which saves time and boosts efficiency.
Aspect Details
Average Cost-Per-Genome Reduction 96% decrease since 2013
Customer Satisfaction Rate 96%
Repair Time Less than 1 day
Technical Support Available 24/5

The NovaSeq platform offers high read counts and finds more unique OTUs. It’s a top choice because of its superior performance. It provides high-quality data and analysis, all at a reasonable price.

Real-World Impact of the NovaSeq Sequencing Platform

Illumina’s NovaSeq platform has changed the game in Large-Scale Genomic Projects. It has made genetic research faster and cheaper. This has opened up new ways to discover things.

The cutting-edge technology in the NovaSeq X Series lets you sequence lots of genomes at once. You can sequence over 128 human genomes or more than 1,000 transcriptomes in one go. This is key for big projects where you need lots of data to find new treatments.

In clinics, the NovaSeq platform has also made a big difference. It can sequence up to 16 terabases per run. This means doctors can find genetic mutations and give better treatments.

UMIs (Unique Molecular Identifiers) in the NovaSeq platform help keep data clean. They remove duplicates without losing important information. This makes genetic tests more reliable and helps in personalized medicine.

Studies with NovaSeq 6000, NovaSeq X, Element Biosciences AVITI, and Singular Genomics G4 show better results. They help find genes and get accurate gene expression profiles, especially with more than 125 ng input. Even with less input, quality stays high.

The NovaSeq platform has a huge impact on genetic research and medicine. It shows how important new sequencing tech is for Large-Scale Genomic Projects and personalized medicine.

User Experiences and Reviews of the Illumina NovaSeq

The Illumina NovaSeq series has won praise in the scientific world. It’s known for its innovative design and practical use. Users love its ease of use, improved productivity, and simple operation.

Many reviews talk about the NovaSeq’s ability to handle big sample sizes well. Users say one NovaSeq run can beat many MiSeq runs in quality. They also find it cost-effective, with one user saying it’s cheaper for 1 billion-plus reads than MiSeq.

The NovaSeq X Series is praised for its small footprint and eco-friendly consumables. This makes workflows faster and easier. The fewer steps make it simpler to go from planning to analysis.

Researchers are now using NovaSeq for 16S sequencing, finding it accurate and efficient. Some suggest using Illumina’s indexes or staggered primers to fix issues. They also recommend adding diversity to libraries for better results.

The NovaSeq X Series is not just functional but also beautiful. Its design uses light to guide workflows, blending beauty with practicality. This design has earned it positive reviews for its intuitive interface.

Comparing MiSeq and NovaSeq is recommended. Users suggest downsampling and using mock microbial communities for fair comparisons. This feedback highlights the NovaSeq’s reliability, efficiency, and impact on genetic research worldwide.

Expanding Research Horizons with Multiomics Using NovaSeq

The Illumina NovaSeq platform is special because it lets researchers mix genomics, transcriptomics, and epigenetics. This gives a full view of how biological systems work. By using NovaSeq’s multiomics, scientists can understand complex biological interactions better. This moves their research forward a lot.

For example, a study on lactic acid bacteria (LAB) shows the power of combining data. It gives a clearer picture of LAB’s role in the gut microbiome. This helps scientists understand health and disease better. By combining genomics, transcriptomics, and epigenetics, they find important markers and rules that were hard to see before.

The NovaSeq 6000 System is a big step forward in sequencing technology. For instance:

  • Illumina wants to finish human whole-genome sequencing for $1,000 per genome.
  • These systems can sequence from three to 48 human whole genomes at once. This makes things faster and more efficient.
  • NovaSeq might even make the $100 genome possible someday.

Using NovaSeq to mix genomics, transcriptomics, and epigenetics helps us understand cell differences. For example, it shows how chromatin barriers control cell fate and lineage. This deep research leads to big discoveries in disease understanding and treatment. It shows how important multiomics is in today’s research.

Aspect Details
Sequencing Range 3 to 48 human whole genomes per run
Cost Efficiency Project cost of $1,000 per genome
Pricing $985,000 (NovaSeq 6000); $850,000 (NovaSeq 5000)

Conclusion

The Illumina NovaSeq platform is at the top of sequencing innovation. It can make up to 6 terabases of data and 20 billion reads at once. This makes it better than any other technology, setting new standards in genome analysis.

The NovaSeq 6000 system can sequence a trio in one day or up to 48 genomes in two days. This shows how fast and efficient it is.

High-quality results are what NovaSeq systems are known for. In a human genome run, over 91% of bases were sequenced above Q30. On a single flow cell, it made 1268 Gb of data with 91% of bases above Q30.

Comparative analyses show NovaSeq outperforms HiSeq 2500 and 4000 systems. It gives consistent, concordant, and high-quality data.

The NovaSeq platform can handle up to eight human whole-genome samples or two WGS trio samples on each flow cell. The latest software update, NovaSeq X update 1.2, makes it even better. It can now do up to 16 terabases in a dual flow cell sequencing run and has an empirical error rate of Q40.

With NovaSeq, tens of thousands of whole genomes can be delivered annually. It also has an average of 95% of reads aligning to the reference genome across all samples. NovaSeq achievements are both far-reaching and impactful.

In the end, the Illumina NovaSeq platform changes how we analyze genomic data. It drives healthcare, research, and more with unmatched precision and innovation. For researchers, NovaSeq is not just a tool—it’s a game-changer in genome analysis.

FAQ

What is the Illumina NovaSeq platform?

The Illumina NovaSeq platform is a cutting-edge DNA sequencing technology. It offers rapid, high-throughput capabilities for comprehensive genomic analysis. It supports various applications, including genome sequencing, oncology studies, and research into complex genetic diseases.

How does the Illumina NovaSeq system revolutionize genomic data analysis?

The NovaSeq system provides deep and broad coverage of genetic data. It enables researchers to unlock complex genetic information and gain unprecedented insights into DNA and RNA. Its high-resolution and comprehensive views make it invaluable for advanced research and clinical diagnostics.

What are the main features and specifications of the NovaSeq 6000 system?

The NovaSeq 6000 system is known for its high-throughput sequencing capabilities. It delivers detailed and extensive genetic information efficiently. It supports various sequencing activities with high fidelity and substantial data output, making it ideal for large-scale genomic projects.

What applications can be supported by the Illumina NovaSeq in genetic analysis?

The NovaSeq excels in applications such as whole-genome sequencing, RNA-Seq, epigenetic analysis, and more. It provides detailed insights into genetic transcription, regulation, and complex genetic diseases. This aids groundbreaking discoveries in genetics, health, and disease research.

What are the benefits of using the Illumina NovaSeq for high-throughput sequencing?

The NovaSeq system offers unparalleled scalability and efficiency. It allows researchers to process large datasets at lower costs with higher throughput and speed. This significantly boosts productivity in genomics research by making high-throughput sequencing more accessible and affordable.

How do the NovaSeq 6000 and NovaSeq X Plus systems compare?

Both the NovaSeq 6000 and NovaSeq X Plus systems provide robust sequencing technologies. The X Plus offers enhancements like greater throughput for extensive genomic projects. It can sequence over 128 genomes per run, showing significant technological progress in scalability and performance.

What innovations in sequencing technology are incorporated in NovaSeq?

NovaSeq includes innovations like XLEAP-SBS chemistry for faster and more accurate sequencing. It also has patterned flow cell technology that increases throughput. These innovations reinforce NovaSeq’s leading position in next-generation sequencing technology.

How does the NovaSeq platform handle data analysis?

The NovaSeq platform’s data analysis capabilities are designed to efficiently handle extensive datasets. It allows researchers to perform in-depth analyses and interpret complex genetic information swiftly. Advanced bioinformatics tools further enhance these capabilities.

What is the workflow of the Illumina NovaSeq system?

The workflow of the NovaSeq system includes meticulous library preparation, highly precise sequencing processes, and robust data storage and analysis solutions. This ensures a streamlined and efficient pathway from sample to insight.

Is the Illumina NovaSeq platform cost-effective?

Despite its advanced capabilities, the NovaSeq platform is designed to be cost-effective. It offers scalable options that reduce per-sample costs. This makes high-throughput sequencing more accessible for a broad range of genomic applications.

What impact has the NovaSeq sequencing platform had on real-world genomic projects?

NovaSeq has significantly impacted large-scale genomic projects and clinical applications. It provides high-accuracy, comprehensive data. This enhances genetic research and improves patient outcomes in clinical settings.

What do users say about the Illumina NovaSeq platform?

User reviews of the NovaSeq series highlight its reliability, efficiency, and revolutionary impact on labs worldwide. Scientists across the globe have provided positive feedback and strong endorsements. This underscores its role in advancing genetic research.

How does NovaSeq support multiomics research?

NovaSeq enables multiomics approaches by combining genomics, transcriptomics, and epigenetics. It offers a holistic view of biological systems. These capabilities facilitate comprehensive research, paving the way for significant breakthroughs in understanding complex biological interactions.

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