Eurofins DNA Sequencing
Unlock the secrets of life with Eurofins DNA Sequencing, a global leader in genomic research and DNA analysis. For nearly 40 years, Eurofins has been at the forefront of sequencing services, offering cutting-edge solutions for researchers and healthcare professionals alike1. Their commitment to excellence shines through in their wide array of products, including DNA/RNA Synthesis, Probes, Nanopore Sequencing, Sanger Sequencing, and Genesynthesis1.
With a focus on speed and accuracy, Eurofins Genomics provides nationwide overnight sequencing results, empowering scientists to push the boundaries of genomic research. Their competitive pricing structure, ranging from $0.50 to $4.00 per sample, makes advanced DNA analysis accessible to a broad range of institutions and researchers2. Eurofins’ expertise spans various industries, including Molecular Diagnostics, Academics, Infectious Disease, Life Sciences, Clinical, Agro Science, and Pharma1.
Eurofins’ dedication to customer satisfaction is evident in their personalized approach. They offer tailored solutions, from separate tube submissions to plate reaction options, catering to diverse research needs2. With data delivery typically expected within 24 hours of sample receipt, even on Saturdays, Eurofins ensures that your genomic research stays on track2.
Key Takeaways
- Eurofins offers nearly 40 years of experience in DNA sequencing
- Competitive pricing from $0.50 to $4.00 per sample
- Nationwide overnight sequencing results available
- Tailored solutions for various industries and research needs
- 24-hour turnaround time, including Saturdays
- Wide range of sequencing options and submission methods
What is Eurofins DNA Sequencing?
Eurofins DNA Sequencing is a cutting-edge service that unveils genetic information. This pioneer in genomic analysis has been serving scientists for nearly four decades, offering a range of sequencing technologies1. Their expertise spans from traditional Sanger sequencing to advanced next-generation sequencing methods.
Overview of DNA Sequencing Technologies
Eurofins employs various sequencing techniques to meet diverse research needs. Sanger sequencing, known as the gold standard, boasts an impressive 99.999% accuracy rate with a 97.3% success rate across all applications3. For larger-scale projects, next-generation sequencing offers high-throughput capabilities. Eurofins also provides nanopore sequencing, a fast and cost-effective option for many applications1.
Importance in Research and Healthcare
DNA sequencing plays a crucial role in advancing scientific knowledge and improving healthcare outcomes. In research, it enables discoveries in fields like genetics and evolution. For healthcare, genomic analysis supports personalized medicine, allowing tailored treatments based on individual genetic profiles. Eurofins’ sequencing services are vital in detecting sequence variations, which is particularly important in pharmaceutical research and development1.
| Sequencing Type | Accuracy | Success Rate | Key Advantage |
|---|---|---|---|
| Sanger Sequencing | 99.999% | 97.3% | Gold Standard |
| Next-Generation Sequencing | Variable | High | High-throughput |
| Nanopore Sequencing | Improving | High | Fast and Affordable |
With its commitment to quality and innovation, Eurofins DNA Sequencing continues to push the boundaries of genomic research and its applications in healthcare and beyond.
Benefits of Using Eurofins DNA Sequencing
Eurofins DNA Sequencing offers a wealth of advantages for researchers and professionals in various fields. The company’s commitment to excellence shines through its precise results, quick sequencing, and versatile genomic services.
High Accuracy and Reliability
Eurofins stands out for its exceptional accuracy in DNA sequencing. Their advanced technologies ensure reliable outcomes across diverse applications. The company’s adherence to strict quality control measures at every step of the sequencing process guarantees dependable results4.
Fast Turnaround Times
Speed is crucial in genomic research, and Eurofins delivers. Their quick sequencing services provide rapid results without compromising quality. Delivery times vary based on the service selected, with data delivery guaranteed next business day for different service types like NightXpress, LightRun, PlateSeq, and TubeSeq5.
Wide Range of Applications
Eurofins’ versatile genomic services cater to diverse needs. They offer 80 different standard primers for DNA sequencing orders, enabling a broad spectrum of applications5. Their services span academic research, clinical diagnostics, and commercial sectors, making them a one-stop solution for various genomic needs4.
| Service | Benefit | Application |
|---|---|---|
| GMP Sequencing | Regulatory compliance | Non-clinical research |
| GLP Extraction | Enhanced documentation | Pharmaceutical development |
| Sanger Sequencing | Data security | Clinical diagnostics |
With Eurofins, customers enjoy flexibility in sample storage and data access. DNA samples are stored for 4 weeks, and sequencing data is accessible for 6 months after completion5. This comprehensive approach to genomic services makes Eurofins a trusted partner in advancing scientific research and innovation.
Services Offered by Eurofins DNA Sequencing
Eurofins DNA Sequencing provides a wide array of genomic services to meet diverse research needs. Their offerings cover various sequencing options and DNA analysis techniques, catering to projects of all sizes and complexities.
Next-Generation Sequencing (NGS)
Eurofins’ NGS services utilize cutting-edge technology for high-throughput DNA analysis. This advanced sequencing option enables researchers to obtain comprehensive genomic data quickly and efficiently. NGS is particularly useful for large-scale projects requiring detailed genetic information.
Sanger Sequencing
The Sanger sequencing service at Eurofins boasts an impressive 99.999% accuracy and a 97.3% success rate across all applications3. This gold standard approach is ideal for targeted DNA analysis and smaller-scale projects. Eurofins offers free Q20, Q30, or Q40 monitored single strand data, enhancing the reliability of results6.
Whole Genome Sequencing
Whole genome sequencing provides a complete picture of an organism’s genetic makeup. Eurofins offers this comprehensive service with read lengths of up to 1,100 bases, allowing for in-depth DNA analysis6. Their whole genome sequencing capabilities are crucial for understanding complex genetic traits and diseases.
Eurofins stands out as the fastest nationwide sequencing provider, outperforming competitors in quality metrics like read length and Q20 score3. They offer overnight results throughout the continental US, typically delivering by 10 AM on the day samples arrive3. This rapid turnaround, combined with their range of sequencing options, makes Eurofins a top choice for researchers and institutions seeking reliable genomic services.
Eurofins DNA Sequencing Technology
Eurofins DNA Sequencing Technology stands at the forefront of genomic research, employing state-of-the-art sequencing methods and advanced data analysis tools. The company’s commitment to quality assurance ensures reliable results for researchers and clinicians alike.
Cutting-Edge Instruments
Eurofins Genomics boasts an impressive array of sequencing systems, including the HiSeq 2000 for processing complex genomes and numerous samples7. Their equipment lineup features Illumina MiSeq, HiSeq 2000/2500, and Life Technologies Ion Proton for high-throughput analysis, enabling efficient processing of single samples to thousands of samples in batch mode7.
Advanced Bioinformatics Solutions
The company’s state-of-the-art sequencing capabilities are complemented by sophisticated bioinformatics solutions. Eurofins Genomics collaborates with Igenbio for specialized sequencing and analysis services, particularly for microbial, fungal, and algal organisms7. This partnership enhances their data analysis capabilities, providing comprehensive insights for various research applications.
Quality Control Measures
Eurofins Genomics maintains stringent quality control measures throughout its sequencing processes. The company is certified according to ISO:9001 and ISO:17025, ensuring high standards in their genomic services7. They have also achieved GLP certification for DNA sequencing services, making them the first genomics service provider in Germany to do so7. These certifications underscore Eurofins’ commitment to quality assurance in their sequencing technologies.
| Sequencing System | Application | Capacity |
|---|---|---|
| HiSeq 2000 | Complex genomes | High-throughput |
| Illumina MiSeq | Targeted sequencing | Medium-throughput |
| Ion Proton | Exome sequencing | Fast turnaround |
With over 300 genomics experts globally, including more than 80 PhDs in various genomics-related disciplines, Eurofins Genomics continues to push the boundaries of DNA sequencing technology8. Their advanced sequencing capabilities, coupled with rigorous quality control, position them as a leader in the field of genomic research and applications.
Applications in Medical Research
Eurofins DNA Sequencing plays a vital role in advancing medical research across various fields. The company’s cutting-edge technologies support groundbreaking studies in personalized medicine, clinical diagnostics, and cancer research.
Personalized Medicine
Genetic testing has revolutionized personalized medicine approaches. Eurofins’ advanced sequencing techniques help researchers identify specific genetic markers linked to diseases, enabling tailored treatment plans. For example, antisense oligonucleotides show promise in treating genetic disorders like spinal muscular atrophy9.
Clinical Diagnostics
Molecular diagnostics benefit greatly from Eurofins’ DNA sequencing services. Techniques like Fluorescent In Situ Hybridization (FISH) use oligonucleotide probes to detect specific DNA sequences, aiding in cancer diagnostics and genetic disorder screening9. In 2021, exome sequencing was used to investigate histopathology, genotype, and postsurgical outcomes in patients with primary aldosteronism10.
Cancer Research
Eurofins’ sequencing capabilities contribute significantly to cancer research. Whole-genome sequencing allows researchers to scrutinize entire genomes, helping identify disease-associated variants11. A 2023 study used plasma cell-free DNA methylation analysis for ovarian cancer detection, showcasing the potential of advanced sequencing in early diagnosis10.
By providing high-quality sequencing data, Eurofins supports disease research across multiple fronts. From studying gene function to developing novel therapeutics, their services accelerate medical breakthroughs and improve patient outcomes.
Eurofins DNA Sequencing in Agriculture
Eurofins DNA Sequencing plays a crucial role in modern agroscience. The company’s advanced technologies drive crop improvement and enhance livestock genetics, paving the way for sustainable farming practices.
Genomic Testing for Crops
Eurofins Genomics offers comprehensive DNA sequencing services for plant breeders. Their cutting-edge technologies include whole genome sequencing and high-density microarrays for DNA marker discovery12. These tools enable precise genetic analysis, facilitating the development of resilient and high-yielding crop varieties.
The company’s genotyping platforms provide high accuracy and speed for marker-assisted selection in plant breeding12. This approach allows breeders to identify desirable traits quickly, accelerating the crop improvement process. Eurofins also offers cost-effective NGS-based and qPCR-based solutions for plant breeding projects12.
Animal Breeding Techniques
In livestock genetics, Eurofins Genomics delivers powerful tools for genomic selection. They optimize Illumina and Thermo Fisher Scientific microarray platforms to enhance breeding programs12. These services help farmers improve herd health and productivity.
For aquaculture, Eurofins provides specialized solutions. These include marker discovery, breeding and selection tools, and pathogen screening for aquatic species12. Their expertise in qPCR assay development allows for scalable testing capacity in pathogen detection, crucial for maintaining healthy aquaculture stocks12.
| Service | Application | Benefit |
|---|---|---|
| Whole Genome Sequencing | Crop Improvement | Detailed genetic analysis |
| Microarray Platforms | Livestock Breeding | Enhanced genomic selection |
| qPCR Assays | Aquaculture | Efficient pathogen detection |
Eurofins Genomics has established itself as a trusted global brand for agrigenomics, offering tailored end-to-end service solutions for specific breeding project needs12. Their commitment to advancing agroscience through DNA sequencing continues to drive innovation in agriculture worldwide.
Customer Support and Consultation
Eurofins DNA Sequencing offers top-notch customer support and consultation services to ensure a smooth experience for clients. Their team of experts provides guidance throughout the sequencing process, from sample submission to data interpretation13.
Expert Guidance Throughout the Process
Clients benefit from dedicated project managers and study directors who offer comprehensive technical assistance and project consultation13. This support includes help with DNA/RNA extraction, genotyping, and various analysis services. Eurofins’ professionals also assist with assay development, validation, and result interpretation13.
FAQs for Clients
To address common concerns, Eurofins provides a range of client resources, including FAQs and troubleshooting guides. Here’s a table outlining some frequent sequencing issues and their solutions:
| Issue | Cause | Solution |
|---|---|---|
| Failed DNA Sequencing | Low DNA template concentration | Check concentration by agarose gel14 |
| Double Sequence Data | PCR products not purified | Check PCR purification protocol14 |
| Noisy Background | Clone contamination | Return to clone resource14 |
| Mid Sequence Stop | Secondary structures in template | Use Power Read technology14 |
Eurofins’ commitment to quality is evident in their ISO 9001, ISO 13485, and ISO 17025 accreditations, covering molecular testing methods and Good Laboratory Practice (GLP)13. This ensures clients receive reliable results and expert support throughout their sequencing projects.
Pricing and Packages
Eurofins offers affordable sequencing solutions with flexible packages to meet diverse research needs. Their cost-effective genomics services cater to various project scales and budgets, ensuring accessibility for researchers and institutions alike.
Competitive Pricing Structure
Eurofins’ pricing reflects their commitment to making DNA sequencing accessible. For instance, their DNA synthesis options range from $0.30 for 10 nmole to $19.95 for 10 umole, while RNA synthesis starts at $5.25 for 50 nmole15. The SimpleSeq™ Prepaid Sequencing Kit, priced at $554.40, includes 96 virtual sequencing credits and barcoded tubes, with 96% of results delivered the same day samples arrive at the lab16.
Customizable Options for Various Needs
Eurofins provides a wide array of customizable options to suit different project requirements. Their services include:
- DNA and RNA synthesis at various scales
- Express products for faster turnaround
- Specialized options like LNA bases and qPCR probes
- Multiple purification methods for DNA oligos
For high-throughput needs, Eurofins offers next-generation sequencing services using advanced instruments. Their pricing structure accommodates different user types, with costs varying for internal, external academic, and non-academic users17.
| Service | Internal UT Users | External Academic Users | External Non-Academic Users |
|---|---|---|---|
| Genome Library Prep (per sample) | $42 – $65 | $53 – $82 | $65 – $100 |
| Full Amplicon Library Prep (49-96 samples) | $1,700 | $2,125 | $2,550 |
| Illumina iSeq Sequencing | $790 | $840 | $890 |
With these flexible packages and competitive pricing, Eurofins ensures that researchers can access high-quality DNA sequencing services without breaking their budgets. Their Mix2Seq Kits offer a convenient prepaid sequencing solution for premixed samples, further streamlining the process for cost-effective genomics research.
Testimonials and Success Stories
Eurofins DNA Sequencing has garnered praise from researchers and institutions worldwide. Their services have led to significant breakthroughs in various fields, showcasing the impact of high-quality sequencing on research outcomes.
Case Studies Highlighting Results
One notable success story involves Eurofins’ contribution to gene therapy advancements. By combining Oxford Nanopore Technology with their sequencing expertise, Eurofins provided AAV sequencing for vector genome integrity analysis, full-length capsid sequencing, and epigenetic profiling18. This service has accelerated progress in developing novel gene therapies.
In another groundbreaking study, Eurofins Forensic utilized ultra-deep next-generation sequencing and bioinformatics to identify genetic differences in identical twins19. This research successfully identified five Single Nucleotide Polymorphisms (SNPs) between identical twins, providing a solution to complex paternity and forensic cases19.
Feedback from Researchers and Institutions
Client satisfaction is evident in the numerous positive testimonials received by Eurofins. Researchers consistently praise the quality of reads, user-friendly experience, and exceptional customer support18. The sequencing success rate is impressive, with Eurofins delivering 210 Mb of ONT sequencing data for standard samples and 360 Mb for big sequences18.
The research impact of Eurofins’ services is further highlighted by their quick turnaround times. Bacterial Genome sequencing results are typically available within 2 business days, extending to 1 week if extraction is required18. This efficiency has been crucial in accelerating research projects across various fields.
| Service | Client Feedback | Impact on Research |
|---|---|---|
| AAV Sequencing | High-quality results, user-friendly | Accelerated gene therapy development |
| Identical Twin Testing | Innovative solution, peer-reviewed | Breakthrough in forensics and paternity testing |
| Bacterial Genome Sequencing | Fast turnaround, reliable data | Expedited microbiology research |
These testimonials and success stories underscore Eurofins’ commitment to delivering high-quality sequencing services that drive research forward and solve complex scientific challenges.
Getting Started with Eurofins DNA Sequencing
Embarking on your DNA sequencing journey with Eurofins is a straightforward process. The company offers a user-friendly sample submission system, ensuring a smooth sequencing workflow from start to finish. Let’s explore how to get your project underway and what to expect during the process.
How to Submit a Sample
Submitting your sample to Eurofins is hassle-free. You can choose between tube or plate formats for your samples. Eurofins provides convenient dropbox locations with free shipping for over 90% of orders, saving you $20 to $34 compared to other providers20. To begin, select either “Manual Entry” or “Upload File” to input your sample details21. For plasmid samples, a common choice, Eurofins offers free use of Universal Primers, enhancing cost-effectiveness21.
Expected Timeline and Process
Eurofins’ sequencing workflow is designed for speed and efficiency. For orders up to 192 standard sequencing reactions, they offer overnight sequencing with results delivered the next day, including Saturdays20. This rapid turnaround is a significant improvement from the early days of DNA sequencing when it took 50 years after DNA’s structure discovery to sequence the human genome22. Today, using next-generation sequencing (NGS), Eurofins can process over 4 billion DNA strands in about six days22.
The process involves three main steps: library preparation, sequencing and imaging, and data analysis22. Eurofins provides clear guidelines throughout, ensuring you’re supported at every stage. Remember to use the provided UPS envelopes with prepaid shipping when submitting your samples21. With Eurofins’ efficient system, you can expect quick results delivery, typically in less than 24 hours on business days for SimpleSeq kit users21.
Q&A
What is Eurofins DNA Sequencing?
Eurofins DNA Sequencing is a leading provider of genomic services with nearly 40 years of experience. They offer fast, accurate, and reliable DNA sequencing solutions for research and healthcare applications, utilizing technologies like Sanger sequencing and next-generation sequencing (NGS).
How accurate is Eurofins DNA Sequencing?
Eurofins DNA Sequencing offers high accuracy with 99.999% precision in Sanger sequencing, which is considered the gold standard. They also maintain a 97.3% success rate across various applications.
What is the turnaround time for Eurofins DNA Sequencing?
Eurofins provides the fastest nationwide sequencing with overnight results for most locations. For most tube orders, overnight sequencing results are available.
What types of sequencing services does Eurofins offer?
Eurofins offers a comprehensive range of sequencing services, including Sanger sequencing, next-generation sequencing (NGS), whole genome sequencing, GLP and GMP sequencing for regulated studies, direct colony sequencing, and various prepaid sequencing options like SimpleSeq, Mix2Seq, and FlexReads.
What industries can benefit from Eurofins DNA Sequencing services?
Eurofins DNA Sequencing services cater to various industries, including medical research, healthcare, agriculture, pharmaceutical development, and academic research. Their services support applications in personalized medicine, clinical diagnostics, cancer research, crop improvement, and animal breeding.
How does Eurofins ensure the quality of its sequencing results?
Eurofins utilizes cutting-edge sequencing instruments, proprietary DNA synthesis technology, and advanced bioinformatics solutions. They employ stringent quality control measures, including process control and QA frameworks, especially for GLP and GMP sequencing, ensuring reliable and reproducible data.
What customer support does Eurofins provide?
Eurofins provides comprehensive customer support and consultation services, including expert guidance throughout the sequencing process, technical support via phone and email with extended hours, and online resources such as FAQs, sample submission guidelines, and a sequencing dashboard for efficient project management.
How does pricing work for Eurofins DNA Sequencing services?
Eurofins offers competitive pricing with a variety of prepaid sequencing options, including SimpleSeq, Mix2Seq, and FlexReads. They provide customizable packages to suit different project needs and budgets. Quotes can be submitted and reviewed through their online quoting tool.
How do I submit a sample for sequencing to Eurofins?
Clients can submit samples in tubes or plates. Eurofins offers convenient dropbox locations for sample submission with free shipping. They provide clear guidelines and support throughout the process, ensuring a smooth experience for clients.
What technologies does Eurofins use for DNA sequencing?
Eurofins utilizes various technologies, including Sanger sequencing and next-generation sequencing (NGS). They employ cutting-edge sequencing instruments and proprietary DNA synthesis technology, along with advanced bioinformatics solutions for data analysis and interpretation.
